Cosmetics for the melasma treatment: study of the dispensation and production in manipulation pharmacy
DOI:
https://doi.org/10.18227/hd.v2i2.7514Keywords:
Melasma, treatment, cosmeticsAbstract
Introduction: Melasma is a cutaneous hyperpigmentation with a higher prevalence in women. Several substances are used for the melasma treatment. The main action mechanism of these substances is depigmentation by removal of the cells with high concentration of melanin or the blocking of melanin formation. Nevertheless, there is still no consistent treatment for this cutaneous alteration. Objective: Evaluate the manipulation of cosmetics with containing depigmenting agents for the melasma treatment, in a manipulation pharmacy in the São José do Rio Pardo city, São Paulo state, at the period from July to December 2016. Methods: It was performed the evaluation of personalized medical prescriptions and internal formulations produced in magisterial pharmacy. The following parameters were evaluated: quantity of medicines produced per month and manipulated substances. Results: In the study period, 803 cosmetic formulations containing depigmenting actives were prepared. The substances used were: hytic acid, mandelic acid, antipolon Ht, belides, skin whitening complex, vitamin C and alpha arbutin. The preparation of two internal formulations (1 and 2) was also evaluated, and formulation 1 (retinoic acid, hydroquinone and clobetasol) presented higher dispensation than formulation 2 (kojic acid and glycolic acid). The winter months and early spring showed the larger production of cosmetics for melasma. Conclusion: The higher demand of cosmetics for melasma treatment presented both depigmenting agent and acids for epithelial desquamation, being produced in greater numbers in the winter months.
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