Gullain-Barré Syndrome cases associated with Zika virus infection in Brazil: a systematic review
DOI:
https://doi.org/10.18227/hd.v4i1.7516Keywords:
Zika virus, Gullain-Barré, infection, Brazil, epidemiologyAbstract
Introduction: Zika is an arbovirus transmitted to humans mainly during the hematophagy of the Aedes aegypti and Aedes albopictus vectors. In most cases, the infection is accompanied by dengue-like symptoms, but studies have correlated it with Guillain-Barré syndrome. Objective: Elaborate a systematic review of cases of Guillain-Barré syndrome that were associated with Zika infections in Brazil from 2013 to 2018. Methods: A survey was conducted at PUBMED using the keywords Zika Virus, Gullain-Barré, Infection, Brazil and Epidemiology. In addition to these words, the following filters were used: study period from 2013 to 2018; full availability of work free of charge; works performed only with human beings; works published in English and Portuguese; and type of article, which included case reports, classic articles, clinical study, clinical trial, comparative study, controlled clinical trial, bibliographic reviews and systematic reviews. Results: Among the eight selected studies, 75% are review articles, one of which is a meta-analysis, 12.5% reported by cases and 12.5% study prospective observational cohort. 470 cases of Guillain-Barré Syndrome associated with Zika infection have been reported. The cases were defined clinically and / or by laboratory methods (serological and molecular). The main limitation for the association was the laboratory diagnosis. Conclusion: It is concluded that even with several difficulties in determining the possible relation-ship, the northeast and southeast were the regions that most published / reported on the cases of GBS associated with ZIKV infection in Brazil.
Downloads
References
ALI, Sofia et al.. Environmental and Social Change Drive the Explosive Emergence of Zika Virus in the Americas. PLoS neglected tropical diseases, v. 11, n, 2, Fev 2017.
ARAUJO, Lucas Masiêro; FERREIRA, Maria Lucia Brito; NASCIMENTO, Osvaldo JM. Guillain-Barré syndrome associated with the Zika virus outbreak in Brazil. Arq. Neuro-Psiquiatr., São Paulo , v. 74, n. 3, p. 253-255, Mar. 2016.
AZEVEDO, Raimunda S. S. et al.. Zika Virus Epidemic in Brazil. II. Post-Mortem Analyses of Neonates with Microcephaly, Stillbirths, and Miscarriage. Journal of Clinical Medicine, v. 7, n. 496, p.1-13, 2018.
BARBI, Ludovica et al. . Prevalence of Guillain-Barré syndrome among Zika virus infected cases: a systematic review and meta-analysis. Braz J Infect Dis, Salvador, v. 22, n. 2, p. 137-141, Mar. 2018.
BRITO, Carlos Alexandre Antunes de; CORDEIRO, Marli Tenorio. One year after the Zika virus outbreak in Brazil: from hypotheses to evidence. Rev. Soc. Bras. Med. Trop., Uberaba , v. 49, n. 5, p. 537-543, Oct. 2016.
FREIRE, Caio César de Melo et al. . NS1 codon usage adaptation to humans in pandemic Zika virus. Mem. Inst. Oswaldo Cruz, Rio de Janeiro , v. 113, n. 5, e170385, 2018.
LEONHARD, Sonja Emily et al.., Zika virus infection in the returning traveller: what every neurologist should know. Practical Neurology, v 18, Abr 2018.
MALONE, Robert W et al.. Zika Virus: Medical Countermeasure Development Challenges. PLoS neglected tropical diseases vol. 10, n. 2 Mar. 2016.
NICASTRI, Emanuele, et al.., Three cases of Zika vírus imported in Italy: need for a clinical awareness and evidencebased knowledge. BMC Infectious Diseases, v. 16, n. 669, 2016.
NOBREGA, Martha Elizabeth Brasil Da. Surto de síndrome de Guillain-Barré possi-velmente relacionado à infecção prévia pelo vírus Zika, Região Metropolitana do Recife, Pernambuco, Brasil, 2015. Epidemiol. Serv. Saude, Brasília, v. 27. n. 2, 2018.
PINHEIRO, Talys J. et al. . Neurological manifestations of Chikungunya and Zika infec-tions. Arq. Neuro- Psiquiatr., São Paulo , v. 74, n. 11, p. 937-943, Nov. 2016.
PLOURDE, AR; BLOCH, EM. A Literature Review of Zika Virus. Emerging Infec-tious Diseases, v. 22, n. 7, 2016.
POSSAS, Cristina et al. . Zika puzzle in Brazil: peculiar conditions of viral introduction and dissemination – A Review. Mem. Inst. Oswaldo Cruz, Rio de Janeiro , v. 112, n. 5, p. 319-327, May 2017.
POSSAS, Cristina. “Zika: what we do and do not know based on the experiences of Brazil. Epidemiology and health. vol. 38 e2016023. 31 May. 2016.
ROSÁRIO, Mateus Santana do et al.. “Guillain-Barré Syndrome After Zika Virus Infec-tion in Brazil.” The American journal of tropical medicine and hygiene, v. 95, n. 5, 2016.
SILVA, Ivan Rocha Ferreira da et al.. “Neurologic Complications Associated With the Zika Virus in Brazilian Adults.” JAMA neurology, vol. 74, Agosto. 2017.
WHITE, Martyn K et al.. Zika virus: An emergente neuropathological agent. Annals of neurology, v. 80, n. 4, p. 479-489, 2016.
WONG, Sanson Sai Wing; POON, Rosana Wing-Shan; WONG, Sally Cheuk-Ying. Zika virus infection— the next wave after dengue? Journal of the Formosan Medical Association, v 115, cap 4, p. 226-242, Abr 2016.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Este obra está licenciado com uma Licença Creative Commons Atribuição 4.0 Internacional.
